Acute Kidney Injury with Hemoptysis: A Formidable Clinical Challenge
Granulomatosis with polyangiitis (GPA), formerly known as Wegner’s granulomatosis, is one of three ANCA-related vasculitides. An environmental trigger in genetically susceptible individuals results in the production of pathogenic antibodies, anti-neutrophil cytoplasmic antibodies (ANCAs).
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Acute Kidney Injury with Hemoptysis – A Formidable Challenge for a Clinician
Granulamatosis with polyangitis (GPA), previously known as Wegner’s granulamatosis is one of the three ANCA associated vasculitis. The pathogenesis involves an environmental trigger in a genetically susceptible individual resulting in the production of pathogenic antibodies, antineutrophil cytoplasmic antibodies (ANCAs), leading to necrotising small and medium vessel vasculitis.
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