1. Can linagliptin be crushed?
Linagliptin, a second-line DPP4 inhibitor, is usually given in a dosage of 5mg once daily. It is a white to the yellowish hard tablet. This tablet is to be consumed orally once a day with or without food. It can be crushed as it is hard and dispersed in water for consumption.
2. Does it cause hypoglycemia?
Linagliptin does not by itself cause hypoglycemia; however, when consumed in combination with other drugs, it may cause hypoglycemia. Linagliptin in combination with other anti-diabetic drugs such as gliclazide and insulin may cause hypoglycemia.
3. How does linagliptin work?
Linagliptin is a class of medications called dipeptidyl peptidase-4 (DPP-4) inhibitors. It acts by increasing the amount of insulin and helps in lowering blood sugar when there is a steep rise in it. It works best when combined with a proper diet, exercise, and other drugs that control blood sugar levels.
4. Is linagliptin better than metformin?
Linagliptin and metformin are used as combinational drugs, to treat patients with diabetes mellitus. Studies done individually, with linagliptin and metformin, did not show significant differences, but linagliptin was more convenient for the treatment of diabetic patients with kidney problems as Linagliptin is not excreted through the kidney. Metformin, on the other hand, is excreted through the kidneys and cannot be prescribed to diabetic patients with kidney problems.
5. Is linagliptin safe in renal failure?
Yes, linagliptin is safe for renal failure patients. Unlike other anti-diabetic medicines, such as sitagliptin and metformin, linagliptin is metabolized and excreted through non-renal ways, through the hepatobiliary route. Hence, it does not burden the kidneys and can also be used without dose adjustments. On patients suffering from chronic kidney disease.
6. How long is linagliptin safe?
Linagliptin can be taken for several years, without any side effects. It can even be taken life-long but, with time it may become less effective in controlling blood sugar levels. In such a case, the doctor might suggest an alternative treatment. Discontinuation of linagliptin should be done under a doctor’s consultation.
7. Is linagliptin better than sitagliptin?
Studies show that Linagliptin and Sitagliptin showed similar efficacy, and no significant difference was found between the two. They can be used interchangeably, depending on the cost and availability. But, studies have shown that linagliptin is preferred by patients suffering from kidney problems as it is eliminated by other routes than kidneys.
8. Is linagliptin 10 a higher dose?
Linagliptin is a medication used to control glycemic index along with proper diet and exercise. The recommended dosage. Is 5mg once a day with or without food. This dosage has been selected according to the clinical trial reports. However, a higher dosage of 10 mg might not cause any adverse effects, it is advisable to consult your doctor regarding the change of dosage.
9. Can I take metformin and linagliptin together?
Studies have shown that linagliptin, in combination with metformin, works well in regulating glycemic index together rather than taken individually. Like other DPP-4 inhibitors, linagliptin is sold in a single pill formulation with metformin. They are effective together, because of their complementary effects. Linagliptin inhibits the DPP-4 enzyme, which enhances glucose-dependent insulin secretion but the mechanism of action of metformin is not dependent on insulin secretion.
10. What is the best time to take linagliptin?
Linagliptin an anti-diabetic medication is consumed orally with or without food. It is consumed once a day and has to be taken at the same time every day for best results. It is used singly or in combination with other drugs to increase effectiveness. The prescription label given by the doctor should be followed for the best results.
Book an appointment or Get a free second opinion from our experts at Yashoda Hospitals today.
