1. How to take Teneligliptin?
Doctors prescribe a 20mg dosage of teneligliptin for adults. You must take the dose only once daily. If needed, your doctor may increase the dosage to 40 mg. Even then, it is administered as a single dose, once a day. Take the tablet orally with water after meals.
2. Is Teneligliptin FDA-approved?
Teneligliptin was approved for usage in Japan in 2012 and Korea in 2014. Argentina and India have also approved it. However, it has not cleared approvals in the USA or areas of Europe. In 2007, it was registered for Phase 1 clinical trials for USFDA. In 2009, it was registered for Phase 2 clinical development with the European Medicines Agency. Both are still underway.
3. When to take Teneligliptin?
You should take teneligliptin in the earlier part of the day. However, since it is long-lasting with minimal chances of hypoglycemia, you can safely take it in the evening too. Teneligliptin is often the choice of drug when metformin, another first-line anti-diabetic, does not give the desired glycaemic control. For ideal results, have it after lunch.
4. Can Teneligliptin be taken twice a day?
No. You should take teneligliptin only once a day. It is made up of DPP-4 molecules that have slow-release and long-lasting properties. Therefore, the optimal dosage is 20 mg to avoid an overdose. Even if the dosage is adjusted to 40 mg in special cases, it is prescribed for consumption once a day.
5. How long doesTeneligliptin take to act?
Studies show that it takes teneligliptin 12 weeks to show a noticeable decrease in HbA1c levels and fasting blood glucose levels. After 12 weeks, there is a 0.8–0.9% reduction in HbA1c levels. The efficacy further improves after 24 weeks. After 52 weeks, there is a clear improvement in both HbA1c and fasting plasma glucose levels with teneligliptin.
6. Is teneligliptin better than metformin?
As the only choice of drug for a monotherapy treating type 2 diabetes mellitus, teneligliptin has better efficacy in reducing HbA1c (hemoglobin A1c i.e., glucose attached to hemoglobin) levels compared to metformin. As a choice of combination therapy, teneligliptin with metformin is more effective than metformin with glimepiride.
7. Does Teneligliptin help with weight loss?
As the only choice of drug for a monotherapy treating type 2 diabetes mellitus, teneligliptin has better efficacy in reducing HbA1c (hemoglobin A1c i.e., glucose attached to hemoglobin) levels compared to metformin. As a choice of combination therapy, teneligliptin with metformin is more effective than metformin with glimepiride.
8. How safe is Teneligliptin?
Teneligliptin is not directly helpful for weight loss. Unlike some other diabetes medication, it causes weight gain as a side effect. Teneligliptin improves glycaemic control and controls blood sugar levels over the long term. This, on the other hand, can help with weight loss.
9. What is the best time to take Teneligliptin?
Teneligliptin can be consumed on an empty stomach or even after a meal. You must ideally take it in the earlier part of the day, as it is a slow-release drug, and because it inhibits the DPP-4 enzyme, which is more active during the daytime than at night.
10. Is Teneligliptin safe in cases of renal failure?
Yes, teneligliptin is safe for patients with renal failure or even end-stage renal disease. For patients suffering from type 2 diabetes mellitus with renal complications, teneligliptin is the better option. Studies show that teneligliptin provides optimal glycaemic control without major dosage changes. A once-daily dosage has proven effective even for T2DM patients with renal complications.
If you’re unsure about how best to treat your type 2 diabetes, consult our specialists at Yashoda Hospitals. As a center of excellence backed with the trust and faith of people for three decades, we have encouraged our doctors to push the limits of excellence. Book a consultation to understand how teneligliptin can help you.
